Product

Pharmaceutical Liquid Mixing Tank

Definition

A Pharmaceutical Liquid Mixing Tank (also known as a blending tank or stirring tank) is generally a vertical mixing vessel. It primarily achieves process production requirements by agitating materials through the tank’s stirring operation. This equipment serves as a necessary device for intermediate buffering, liquid storage, stirring, blending, and reaction in industries such as pharmaceutical, bioengineering, and food production.

Structure

A pharmaceutical liquid mixing tank (vacuum blending tank) is typically composed of the tank body (cylinder), tank cover (head), jacket or coil (for heating/cooling circulation), upper mechanical agitator (anchor type, paddle type, turbine type, etc.), transmission device (motor-reducer), shaft seal device (mechanical seal), supports (platform, legs), and thermal insulation media. The system configuration of the tank mainly includes transmission devices, mechanical seal devices, temperature control devices, cooling devices, as well as weighing and metering devices, liquid level metering devices, etc.

Functions

A pharmaceutical liquid mixing tank features functions such as heating, cooling, thermal insulation, stirring, and metering. According to production and process requirements, it can be designed with heating/cooling systems, low/high-speed stirring systems, sealed pressure-bearing systems, vacuum systems, and metering systems. For different stirred materials and required stirring effects, the structure of the agitator can be adjusted, including turbine type, paddle type, anchor type, frame type, ribbon type, magnetic agitator, etc. Depending on the material ratio and state, weighing batching, flow metering, or liquid level metering can be selected for batching operations.

Nozzle Configuration

The tank body is equipped with process nozzles such as a manhole (which can also serve as a solid feeding port), feeding port, discharging port, sight glass, lighting lamp, breathing port, CIP port (equipped with a sanitary universal cleaning ball), SIP port, sterile sampling port, thermometer, temperature sensor, inlet/outlet for hot and cold media, and sampling port.

 

Nozzles can be designed and manufactured according to the process requirements. The connection forms of nozzles include quick-install clamp type, flange type, and threaded type, which can be selected based on process requirements.

Classification

Pharmaceutical liquid mixing tanks are classified by heating methods into electric heating, oil heating, steam heating, and water heating (or cooling) types. Jacket configurations include jacketed type and external half-pipe type, with oil-heated jackets all equipped with flow guiding devices. Agitation types generally include paddle, anchor, frame, ribbon, and wall-scraping agitators. High-speed types such as dispersion impeller, turbine, high-shear, and propeller types are available for customers to select based on processes.

 

Transmission types include ordinary motors, explosion-proof motors, electromagnetic speed-regulating motors, and frequency converters. Speed reducers include cycloidal-pinwheel, worm gear, and planetary stepless speed-varying types. Shaft seals are combined PTFE packing seals and mechanical seals. Discharge forms include ball valves and tank bottom valves.

 

All process openings for inlet/outlet nozzles and their welding points with the inner tank body adopt flanged arc transition technology, featuring smooth surfaces for easy cleaning, no dead corners, and aesthetic appearance, complying with pharmaceutical GMP standards.

Parameter Table

Nominal Volume 100L 300L 500L 1000L 2000L 3000L 5000L 10000L
Inner Diameter (mm) 500 800 900 1100 1400 1500 1800 2100
Heat Exchange Area (㎡) 0.9 2.0 2.7 4.5 7.5 10.0 13.5 22
Agitation Power (KW) 0.55 0.75 1.5 3.0 4.0 5.5 7.5 11.0
Rotational Speed (r/m) Fixed speed or variable frequency speed regulation
Agitation Type Designed and manufactured according to material properties
Working Pressure (Mpa) Designed and manufactured according to process conditions
Working Temperature (℃) 0-200℃
Jacket Heating/Cooling Medium Steam heating/cooling water/other refrigerants (e.g., ethylene glycol, silicone oil)
Metering Method Weighing batching, liquid level metering, or flow metering
Insulation Material Polyurethane/rock wool
Nozzle Configuration Can be custom-designed as required under satisfying conditions
Tank Material SUS304/316L

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