Stainless Steel Silicone Column

The stainless steel silicone column is also called a chromatographic silicone column or a stainless steel chromatography column. Currently, the stainless steel silicone column is used to separate different types or components of plant active ingredients, chemical intermediates, compounds, and other substances from different fillers in the chromatography column under different conditions in a hierarchical manner, so as to obtain the planned effective components or ingredients.

1. Water, organic solutions, acid – base solutions, etc. can be used to flush or back – flush the column to achieve different process purposes.
2. The use cost is relatively high.
3. Commonly used materials: Glass, polypropylene (PP), stainless steel, rubber – lined or PTFE, and organic glass gaskets include silicone, PTFE, silicone – PTFE, and rubber plates. Among them, the stainless steel silicone column is economical and durable, and can be used for 10 years under normal use. Moreover, it is clean and hygienic, easy to clean, does not adhere to materials, and can fully meet the GMP standards.
4. Application scope: Separation of active ingredients of plants and traditional Chinese medicines, refinement of chemical intermediates from effective ingredients of traditional Chinese medicines, and purification of synthetic products.

1. SFDA “Good Manufacturing Practice for Pharmaceutical Production” (2010 Edition)
2. “Code for Design of Clean Rooms in Pharmaceutical Industry” (GB50457 – 2008)
3. GAMP (Good Automated Manufacturing Practice) for Pharmaceutical Production
4. GB150.1 – 150.4 – 2011 “Steel Pressure Vessels”
5. NB/T47003.1 – 2009 “Steel Welded Atmospheric Pressure Vessels”