Product

Buffer Solution Preparation Tank

Overview

The buffer solution preparation tank, commonly known as the solution preparation tank, is a container designed to mix raw materials, additives, auxiliary materials, and supplementary agents (both liquid and solid) according to production instructions and quality ratio requirements to form a liquid preparation. Typically, it is a three-layer vertical fully sealed sanitary clean container, equipped with functions such as heating, cooling, heat preservation, stirring, and mixing.

 

According to process requirements, buffer solution preparation tanks can be classified into:

 

  • Single-layer buffer solution preparation tank: A single-layer tank without heating or cooling functions, primarily for stirring and mixing.
  • Double-layer insulated buffer solution preparation tank: Mainly used for heat preservation, stirring, and mixing, where the materials entering the tank are hot.
  • Three-layer heat exchange insulated buffer solution preparation tank: Equipped with heating or cooling functions, featuring a jacket that allows the passage of heating or cooling media for temperature control. Materials are fully mixed, dissolved, and  blended through the operation of the agitator.

 

The buffer solution preparation tank system typically includes the following configurations:

 

  • Drive device
  • Mechanical seal device
  • Temperature control device
  • Sight lamp and mirror
  • Stirring device
  • Steam inlet
  • Condensate water outlet
  • Material outlet
  • Drain outlet
  • Sampling port
  • 360° universal cleaning ball
  • Optional components: orifice plate filtration device, weighing and metering device, liquid level metering device, etc.

Features

  1. The buffer solution preparation tank is made of sanitary-grade stainless steel 304 or 316L. The tank body adopts a sanitary and aseptic design, and each pipe orifice is formed with a smooth transition through drawing processing to avoid cleaning and material accumulation dead corners caused by direct socket welding, ensuring the reliability and stability of the production process. The inner surface of the tank is mirror-polished, and the outer surface is made of mirror panels or brushed panels, which is hygienic, clean, and beautiful.
  2. All process pipe orifices on the tank adopt sanitary-grade international ISO standard quick-installation chuck interfaces, which are hygienic, free of dead corners, and easy to disassemble. For corrosive materials, corrosion-resistant PTFE gaskets are selected to ensure service life.
  3. The tank is equipped with online cleaning (CIP) and in-situ sterilization (SIP) functions, which are sanitary and clean, meeting the pharmaceutical GMP standards.
  4. The stirring form can be mechanical stirring such as paddle, anchor, frame, disc type, or magnetic stirring or high-shear stirring according to the material characteristics.
  5. The heating jacket can adopt standard jacket type, half-tube type, or honeycomb plate type. The standard jacket has a large heat exchange area, while the half-tube jacket and honeycomb plate jacket have sufficient heat exchange and good flow guiding effect, but the manufacturing is time-consuming. The jacket form is designed according to the material characteristics and heat exchange requirements to ensure the heat exchange effect and save costs.
  6. Temperature display and control system and liquid level display system can be selected as needed. For those with high requirements for automation, level gauges, flowmeters, etc. with remote output control functions can be equipped for PLC control and one-key operation on the touch screen. For conventional requirements, local display and manual control are adopted.
  7. The equipment is sealed with a special sanitary-grade mechanical seal, which is wear-resistant, does not contaminate materials, and has good sealing performance.

Parameter Selection

Nominal Volume 100L 300L 500L 1000L 2000L 3000L 5000L 10000L
Inner Diameter (mm) 500 800 900 1100 1400 1500 1800 2100
Heat Exchange Area (m²) 0.9 2.0 2.7 4.5 7.5 10.0 13.5 22
Stirring Power (kW) 0.55 0.75 1.5 3.0 4.0 5.5 7.5 11.0
Rotation Speed (r/m) Fixed speed or variable frequency speed regulation
Stirring Form Designed and manufactured according to material properties
Working Pressure (MPa) Designed and manufactured according to process conditions
Working Temperature (℃) 0-200°
Jacket Heating/Cooling Medium Steam/cooling water/other refrigerants such as ethylene glycol, silicone oil, liquid nitrogen, etc.
Metering Method Weighing liquid preparation, liquid level metering, or flow metering
Insulation Material Polyurethane/rock wool/aluminum silicate
Nozzle Configuration Designed as needed under satisfied conditions, with in-situ cleaning and sterilization
Tank Material SUS304/316L

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